The slot where your current radio is located would work. I don't like the location as I feel it is too low. As far as getting it work with stock speakers, I see two options:
1) Replace the radio and install a small amplifier to power your speakers or 2) Keep the stock radio and run the tablet output to the Aux input of the radio (if it has that feature).
For a better look and aesthetics, I'd look at doing a custom job. I believe you can order the bezel contain the radio and temperature controls. I'd relocate the temp controls to the lower sections and the tablet to the higher section for better viewing. Just my suggestions.