After what I'm reading here, and the experience with no GPS-delay in other programs, it seems to me that the problem must be an issue in Destinator itself, or the GPS-device compability.
I'm running on an IBM Laptop - Thinkpad R60 with dual processor and 1 GB of RAM. Don't think the hardware should be the problem. Haven't had any chance to try with another GPS-device, I'm using the old Haicom 204 with USB-cable. But it works like a dream with other Navigation programs.