I have had this problem happen before with Topo USA 5.0. However, it only happened on my carpc and not on my desktop. When I tried to go into other things like media or mixer it only showed the home screen, if I pressed anywhere in that area it would show the media/mixer. It didn't seem to have a problem switching between other apps. Like I said though it only messed up on my car and not my desktop. So its probably just a problem on your install of windows or directx casusing the problems, and not really centra. I know I plan on reinstalling everything once 1.5 is released.