I don't think that will work. I know there isn't room for a 2 din display where the stock radio goes, I have a 2000 Silverado, and it has had every setup under the sun. I'm currently using a MEMO 7" touchscreen display with a clever mounting system as my screen, but it took some work to make it usable. You won't be able to fit a screen that size in that slot without either moving your A/C, cutting up your bezel, and creating a lot of work for yourself.
Moving AC overhead would be work, but doable. I installed power windows in my truck and put the controls up there, but it takes some work to make it look clean.