Yes. We're working through the details of one such climate control interface at this moment even in my Automatic Climate Control thread.
As for replicating guages and such, it is very possible. I would download the latest copy of MDX and take a peek. The example skin has some very good examples of engine interface guages. But the limits are really what you can do with graphics. There's a little bit of a learning curve, but it's not that hard. Once you get acquiated with the configuration utility software (which is a great graphics oriented piece of software) for building your skin, you can do A LOT!