Is the GPS receiver on SiRF or NMEA mode. if it's in SiRF mode, iGuidance would not work. iGuidance will only work in NMEA mode.
You can use a program to switch the mode of the receiver. Be very careful as any wrong settings could render your receiver useless. You shouldn't need to change anything except from SiRF to NMEA and vice versa.
The program I use is called WinFast Navigator. It's a pretty cool program all by itself. It is made for my receiver, but works with any GPS receiver.
Yes I have tried it with the other software. It's a serial gps mouse. It works with other software, however when I went to the help section on the iguidance program itself it said that it would only work with the bundle hardware/software package.... and both you and I know that's not always the case, and I'm just trying to see if anyone else has got it to work with this receiver. So far this receiver has been on of the most versatile that I have used, until this point.