I've done them all, including SP2 and except for MSN Messenger (I hate that friggin' thing), and have no issues. I don't think a lot of them were nessasary but oh well. Why are you asking. Are you having space issues? If so after your updates you can go into the windows DIR. and delete all the blue colored folders to save some space. Of course after that you can't uninstall any of the fixes.