I have a Griffin Powermate and I run FP. The rest of my specs are in my signature, if you need them. I have the powermate set to change volume up and down, pause, scroll through the directory list, and play selected song. All of those functions except volume up and down are done via keyboard shortcuts in FP. [I've tried using shortcuts for volume as well, but stopped because of this bug]
When I'm listening to music, everything is fine, works great. When I watch movies or music videos, however, sometimes the Powermate stops working. Well, I think it just stops working the keyboard shortcuts. I switched volume over to master volume so that I dont lose that when this happens at inopportune times. In order to get it back, I have to minimize FP and open the Griffin settings program from the little icon in the task tray. I dont even need to reset the settings, just open the program. I think I dont even have to hit OK, but could be wrong. Just so long as I actually select that as the active program, and then go back to FP, it works again.