I think it's possible, but wouldn't be worth the time or expense it would take to pull it off, IMHO. You may feel differently about that.
Keep in mind that if you retain that screen, you'd be limited to a composite video signal and you'd lose the touchscreen functionality.
Basically none of the internals (including the DVD player) would be retained, and would have to be replaced with PC components.
Practical? Not in the least.