Looking at the pictures...
I assume that things such as USB ports and your analog input ports are all sockets so no biggie, just plug them in and out of the board.
The digital I/O on the bottom of the board I am assuming are basically just holes through the side to put wires through and holes in the top to pass a screw driver through? (Will have to be a long one for your full height board it looks like.)
And are the top ports for ODBII? I think I saw the holes for those in the side to pass the wires through and the top for the screw driver.