The Shuttle can't be integrated as "cleanly" as a custom miniITX install. It's a cube, whereas some miniITX cases are fairly low profile and can be concealed easily.Originally Posted by J187
And then there's also the power requirements. As long as the board and CPU in a Shuttle can operate with 90-150w, it might be easy enough to power with an Opus or M1-atx. Otherwise you have to look to other PSU options (read: more powerful).