Setup 1 seem to work IF you are using on board graphic or low power AGP card.
When using onboard, you must double check wether DDR400 RAM work with it or not. I seen people complaint about that. Better off using DDR333.
Another way to calculate Wattage is single out each of the device add up all of them and compare to the Opus output. How many amp is needed for each particular power rail (5V, 12V). It look like you are using more power on the 5V rail.
Why don't you use mATX mobo instead of full size (unless you already has one laying around.) Does that board work with mobile AMD?
Better yet, email Opus and ask them if the 150W handle your setup.
I don't think 150W can power your setup 2.