I had exactly the same problem ! The solution is to install the Certified WDM drivers available here http://tech.prolific.com.tw/visitor/...?faqid=1398051 and your problems will be gone ! :-)
I'm using my laptop as car pc with xp SP2.
When I'm going to standby modus there's no problem, but when I want to go back (this is with gps mouse globalsat bu303) the laptop crashes.
When I try the stanby without gps it works fine.
I tried this on my desktop at home with gps, and no problem at all.
Can I use another driver??