Is there a way to use a OBD2 software with the ME? (with skin)
No. You can run just about anything you want as an external app though.
'01 Chevy Xtreme Stepside (pics)
FIC K7MNF-64 / Athlon 3200 | 256 DDR | 120 GB 7.2k WD
WinXP Pro | MediaEngine | 12.1 VGA TFT Touch|Creative CIMR-100
350w Vector | 320w mATX PS | Hellroaring BIC95150 | ButterflySDC