I would/will be nice to have a front end work on any platform that air supports. However, you should prolly post this in the general software development forum (if you haven't already) because that is where all the help is. there aren't many devs in this forum and certainly fewer who can help with an AIR project.
What capabilities does AIR have for media playback? somehow I doubt it has a hook into quicktime which is what most Mac FEs use for media playback.