It comes down to performance. The Core 2 Duos have 2 cores and therefore in many applications are faster. For a carPC I don't think you would really notice the difference anyways. The nice thing about this board is that because it will use a mobile processor it puts out less heat, something good for cars. I also like the fact that the board uses a 19V AC plug which means the Carnetix P1900 or P2140 regulator is a good match and there is no need for an actual power supply. Having said all of this I may just get the AOpen MiniPC...