I'm trying to think of things you might need to know for a new setup... i'm sure others will chime in with whatever I missed.
If graphics seem slow you may need to install a video card driver (the built in generic one is very slow). You can also try enabling compiz if its not already enabled...which makes the windows feel snappier and adds some cool effects. Might also want to open the update manager and get everything up to date (may take awhile on a new install). Other then video drivers everything pretty much is good to go out of the box.