Originally Posted by zootjeff
Putting the regulation at the point of the load assures that the proper voltages are delivered to peripherals without the significant voltage drop associated with long runs or the need to use large guage wire to avoid those same drops.
5V is the name of the game for most peripherals. Simple buck regulators that can output 2-3A would work for nearly all peripherals. A larger 5-10A supply might be more appropriate for a group of co-located devices. Proper sequencing of the power may be required for some applications to work properly but I think it's less of an issue than with what I was talking about before with the 12V supply and the M1-ATX.