Multi-monitor support is fairly limited. However, with multiple sound cards, you can run multiple copies of RR (one for each sound card), then have it show on the monitor you want. Whether it goes through speakers or headphones would be a hardware setup thing. I can't say how multiple touchscreen devices will get along with each other on the same machine -- this will vary between the brand/device used.
In any case, you absolutely DO NOT HAVE to remove CF2 from the machine in order to try/play with RR, and even if you like it, you can leave both in the same machine.