each plugin has its own specific settings and instructions on how to get them to work with RR.
I do feel your pain though, there should be a standard method with some rules to follow that make the whole process as easy as possible.
First would be a plugins folder where all plugins should be installed and auto loaded from instead of the put file anywhere you want method. But thats a whole other thread topic.
Best suggestion is to just do what said plugin says to do to get it to work, for each plugin you want to use.