I loaded HD Radio PCR application on a Windows 2000 CPU that has a serial port and the direct connection worked.
Obviously the hardware handshake is not happening to raise the level of the signal line. I will order the cable you referenced in your earlier post. It lists the following:
Supports automatic handshake mode.
Supports Remote wakeup and power management.
The one I have only lists the Remote wakeup and management, not the automatic handshake.
Thanks for the advice.