I have a flip-down Xenarc 700TR in my acura TL. THe dome lights located between both sunvisor mirrors had to be removed (as well as the included sunglass holder). One problem I ran into was that the base dimensions of the screen were actually SMALLER than the dimensions of the car unit, so the install shop had to create a vinyl trim about 3/4" around the screen to maintain a clean look.
Take a look at the pictures in my sig and be sure to TAKE MESAUREMENTS

My little slip-up cost me an extra $120 on the install, for that vinyl.
@KyleYankan, wires were no problem to run at all, this included the USB touch-screen interface, power wires, as well as a thick VGA extension cable I ran all the way from the trunk. Unit mounts with 4 standard screws, and you may have to create a wood "base" for those screws.